Early aggressive therapy for severe extensive ulcerative colitis.

  title={Early aggressive therapy for severe extensive ulcerative colitis.},
  author={De-jun Cui},
  journal={World journal of gastroenterology},
  volume={15 33},
The current ulcerative colitis (UC) treatment algorithm involves a step-up therapeutic strategy, mainly aiming at inducing and maintaining its clinical remission. Although this therapeutic strategy may seem to be cost-efficient and reduce the risk of side effects, recent trials and case reports have shown that top-down therapy using infliximab induces a rapid clinical response, enhances patient quality of life, promotes mucosal healing, reduces surgeries and indirect cost of treatment for… CONTINUE READING

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