Early administration of probiotics alters bacterial colonization and limits diet-induced gut dysfunction and severity of necrotizing enterocolitis in preterm pigs.

@article{Siggers2008EarlyAO,
  title={Early administration of probiotics alters bacterial colonization and limits diet-induced gut dysfunction and severity of necrotizing enterocolitis in preterm pigs.},
  author={Richard H. Siggers and Jayda Siggers and M. -A. -D. Boye and Thomas Thymann and Lars M\olbak and Thomas D Leser and Bent Jensen and Per Torp Sangild},
  journal={The Journal of nutrition},
  year={2008},
  volume={138 8},
  pages={1437-44}
}
Following preterm birth, bacterial colonization and enteral formula feeding predispose neonates to gut dysfunction and necrotizing enterocolitis (NEC), a serious gastrointestinal inflammatory disease. We hypothesized that administration of probiotics would beneficially influence early bacterial colonization, thereby reducing the susceptibility to formula-induced gut atrophy, dysfunction, and NEC. Caesarean-delivered preterm pigs were provided total parenteral nutrition (1.5 d) followed by… CONTINUE READING
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