Early activation markers of human peripheral dendritic cells.

  title={Early activation markers of human peripheral dendritic cells.},
  author={Peter Hellman and H{\aa}kan Eriksson},
  journal={Human immunology},
  volume={68 5},
Two major populations of dendritic cells (DCs), myeloid and plasmacytoid, can be isolated from human peripheral blood, and are distinguished by differential expression of the cell surface markers CD11c and CD123. These two populations of DCs also are different in their expression of Toll-like receptor (TLRs), which are involved in their activation. To investigate the early events during activation of peripheral DCs, the cells were stimulated in vitro with ligands for TLR-4 (as in… CONTINUE READING


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