Early Weanling and Precocious Development of Small Intestine in Rats: Genetic, Dietary or Hormonal Control

  title={Early Weanling and Precocious Development of Small Intestine in Rats: Genetic, Dietary or Hormonal Control},
  author={Ping Chuan Lee and Emanuel Lebenthal},
  journal={Pediatric Research},
Summary: Small intestinal development was followed in rats from 17 to 28 days of age in order to evaluate the interactions of diets, genetic preprogramming, and hormones in influencing developmental changes. Control pups, weaned naturally at 21-24 days, showed a gradual increase in body weight, intestinal length, and segmental mucosal weight, total DNA, and protein content. In contrast, pups weaned at 17 days showed an immediate increase in intestinal length, decrease in lactase, and precocious… CONTINUE READING
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