Early T cell activation correlates with expression of apoptosis markers in patients with end-stage renal disease.

@article{Meier2002EarlyTC,
  title={Early T cell activation correlates with expression of apoptosis markers in patients with end-stage renal disease.},
  author={Pascal Meier and Eric Dayer and Edouard Blanc and J P Wauters},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2002},
  volume={13 1},
  pages={204-12}
}
ABSTRACT. End-stage renal failure (ESRF) and chronic hemodialysis (HD) induce a state of immunodeficiency that involves T cell-mediated responses. A decreased T cell number combined with a reduced T cell lifespan and an increased T cell activation might play a role in the immune impairment associated with ESRF and chronic HD. Increased T cell activation associated with immunodeficiency suggests that activated T cells may be driven to apoptosis. To test this hypothesis, CD3+ T cell activation… CONTINUE READING

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