Early Production of Macrophage Inflammatory Protein-1α Occurs in Respiratory Distress Syndrome and Is Associated with Poor Outcome

@article{Murch1996EarlyPO,
  title={Early Production of Macrophage Inflammatory Protein-1α Occurs in Respiratory Distress Syndrome and Is Associated with Poor Outcome},
  author={Simon H. Murch and Kate L. Costeloe and Nigel Klein and Thomas Macdonald},
  journal={Pediatric Research},
  year={1996},
  volume={40},
  pages={490-497}
}
Although progression to pulmonary fibrosis in preterm infants with respiratory distress syndrome (RDS) is related to the inflammatory response, the nature of this response remains controversial. We have therefore performed sequential bronchoalveolar lavages in 30 infants with RDS (13 of whom developed bronchopulmonary dysplasia) and 7 ventilated control infants, characterizing the cells obtained by immunohistochemical analysis of lineage-specific markers and assaying macrophage-associated… CONTINUE READING