Early Onset of Puberty: Tracking Genetic and Environmental Factors

  title={Early Onset of Puberty: Tracking Genetic and Environmental Factors},
  author={Anne-Simone Parent and Gr{\'e}gory Rasier and Arlette G{\'e}rard and Sabine Heger and Christian L. Roth and Claudio A. Mastronardi and Heike Jung and Sergio R. Ojeda and Jean Pierre Bourguignon},
  journal={Hormone Research in Paediatrics},
  pages={41 - 47}
Under physiological conditions, factors affecting the genetic control of hypothalamic functions are predominant in determining the individual variations in timing of pubertal onset. In pathological conditions, however, these variations can involve different genetic susceptibility and the interaction of environmental factors. The high incidence of precocious puberty in foreign children migrating to Belgium and the detection in their plasma of a long-lasting 1,1,1-trichloro-2,2-bis(4-chlorophenyl… 

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