Early Life Stress Inhibits Expression of a Novel Innate Immune Pathway in the Developing Hippocampus

@article{Wei2012EarlyLS,
  title={Early Life Stress Inhibits Expression of a Novel Innate Immune Pathway in the Developing Hippocampus},
  author={Lan Wei and Arthur A. Simen and Shrikant Mane and Arie Kaffman},
  journal={Neuropsychopharmacology},
  year={2012},
  volume={37},
  pages={567-580}
}
Childhood maltreatment represents a major risk factor for the development of numerous childhood psychopathologies that in many cases linger as chronic mental illnesses in adulthood. Exposing rodents or non-human primates to early life stress increases anxiety-like behaviors and impairs cognitive function in adulthood, suggesting that animal models may provide important insights into parallel developmental processes in humans. Using an unbiased genomic screen, we found that expression of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS