Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System

@inproceedings{Bilbo2009EarlyLifePO,
  title={Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System},
  author={Staci D. Bilbo and Jaclyn M. Schwarz},
  booktitle={Front. Behav. Neurosci.},
  year={2009}
}
The immune system is well characterized for its critical role in host defense. Far beyond this limited role however, there is mounting evidence for the vital role the immune system plays within the brain, in both normal, "homeostatic" processes (e.g., sleep, metabolism, memory), as well as in pathology, when the dysregulation of immune molecules may occur. This recognition is especially critical in the area of brain development. Microglia and astrocytes, the primary immunocompetent cells of the… CONTINUE READING
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