Early-Life Human Microbiota Associated With Childhood Allergy Promotes the T Helper 17 Axis in Mice

@inproceedings{Petursdottir2017EarlyLifeHM,
  title={Early-Life Human Microbiota Associated With Childhood Allergy Promotes the T Helper 17 Axis in Mice},
  author={Dagbjort H. Petursdottir and Sofia Nordlander and Khaleda Rahman Qazi and Claudia Carvalho-Queiroz and Omneya Ahmed Osman and Eva Hell and Sophia Bj{\"o}rkander and Yeneneh Eshetu Haileselassie and Marit Navis and Efthymia Kokkinou and Ivan Zong Long Lio and Julia Hennemann and Bj{\"o}rn Brodin and Douglas L. Huseby and Caroline Nilsson and Diarmaid Hughes and Klas I. Udekwu and Eva Sverremark-Ekstr{\"o}m},
  booktitle={Front. Immunol.},
  year={2017}
}
The intestinal microbiota influences immune maturation during childhood, and is implicated in early-life allergy development. However, to directly study intestinal microbes and gut immune responses in infants is difficult. To investigate how different types of early-life gut microbiota affect immune development, we collected fecal samples from children with different allergic heredity (AH) and inoculated germ-free mice. Immune responses and microbiota composition were evaluated in the offspring… CONTINUE READING
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