Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming.

@article{Granucci2003EarlyIP,
  title={Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming.},
  author={Francesca Granucci and Sonia Feau and Veronique Angeli and François Trottein and Paola Ricciardi-Castagnoli},
  journal={Journal of immunology},
  year={2003},
  volume={170 10},
  pages={5075-81}
}
Dendritic cells (DCs) are professional APCs able to initiate innate and adaptive immune responses against invading pathogens. Different properties such as the efficient Ag processing machinery, the high levels of expression of costimulatory molecules and peptide-MHC complexes, and the production of cytokines contribute in making DCs potent stimulators of naive T cell responses. Recently we have observed that DCs are able to produce IL-2 following bacterial stimulation, and we have demonstrated… CONTINUE READING

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