Early [(11)C]Flumazenil/H(2)O positron emission tomography predicts irreversible ischemic cortical damage in stroke patients receiving acute thrombolytic therapy.

@article{Heiss2000EarlyP,
  title={Early [(11)C]Flumazenil/H(2)O positron emission tomography predicts irreversible ischemic cortical damage in stroke patients receiving acute thrombolytic therapy.},
  author={W-D Heiss and Lutz Kracht and Martin Grond and Jobst Rudolf and Bernd Bauer and Klaus Wienhard and Gunter Pawlik},
  journal={Stroke},
  year={2000},
  volume={31 2},
  pages={366-9}
}
BACKGROUND AND PURPOSE Central benzodiazepine receptor ligands, such as [(11)C]flumazenil (FMZ), are markers of neuronal integrity and therefore might be useful in the differentiation of functionally and morphologically damaged tissue early in ischemic stroke. We sought to assess the value of a benzodiazepine receptor ligand for the early identification of irreversible ischemic damage to cortical areas that cannot benefit from reperfusion. METHODS Eleven patients (7 male, 4 female, aged 52 to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Estimation of ischemic cerebral blood flow using [ 15O]water and PET without arterial blood

  • J Löttgen, U Pietrzyk, K Herholz, K Wienhard, W-D. Heiss
  • 1998

Similar Papers

Loading similar papers…