EXPERIMENTAL GLOMERULONEPHRITIS VI. THE AUTOLOGOUS PHASE OF NEPHROTOXIC SERUM NEPHRITIS

@inproceedings{Unanue1965EXPERIMENTALGV,
  title={EXPERIMENTAL GLOMERULONEPHRITIS VI. THE AUTOLOGOUS PHASE OF NEPHROTOXIC SERUM NEPHRITIS},
  author={Emil R Unanue and F. J. Dixon},
  year={1965}
}
Nephrotoxic serum nephritis was studied in rats receiving variable amounts of kidney-fixing antibody and active or passive immunization to the heterologous gamma globulin of the species supplying the nephrotoxic antibody. Rats injected with a moderate to a large amount of kidney-fixing antibody (180 to 380 µg) and immunized to the heterologous gamma globulin developed a more severe nephritis than rats receiving similar amounts of antibody without further immunization. Rats injected with minimal… CONTINUE READING

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