EXCITATION–CONTRACTION COUPLING FROM THE 1950s INTO THE NEW MILLENNIUM

@article{Dulhunty2006EXCITATIONCONTRACTIONCF,
  title={EXCITATION–CONTRACTION COUPLING FROM THE 1950s INTO THE NEW MILLENNIUM},
  author={Angela F. Dulhunty},
  journal={Clinical and Experimental Pharmacology and Physiology},
  year={2006},
  volume={33}
}
  • A. Dulhunty
  • Published 1 September 2006
  • Biology
  • Clinical and Experimental Pharmacology and Physiology
1 Excitation–contraction coupling is broadly defined as the process linking the action potential to contraction in striated muscle or, more narrowly, as the process coupling surface membrane depolarization to Ca2+ release from the sarcoplasmic reticulum. 2 We now know that excitation–contraction coupling depends on a macromolecular protein complex or ‘calcium release unit’. The complex extends the extracellular space within the transverse tubule invaginations of the surface membrane, across the… 
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