• Corpus ID: 56454905

EVALUATION OF EFFECTS OF RUTIN ON OXIDATIVE STRESS IN DIABETIC RAT

@inproceedings{Bais2012EVALUATIONOE,
  title={EVALUATION OF EFFECTS OF RUTIN ON OXIDATIVE STRESS IN DIABETIC RAT},
  author={S. K. Bais and G Y Shende and Avinash Jiddewar},
  year={2012}
}
Oxidative stress which usually results from excessive production of ROS and/or diminished activity of antioxidants have been implicated as a major contributor to the etiology of severe pathologies, including diabetes. Moreover, increasing evidence shows that excess ROS acts as negative regulators of insulin signaling leading to insulin resistance, a known metabolic abnormality associated with diabetes. Oxidative stress is currently suggested as a mechanism underlying diabetes and diabetic… 
4 Citations

Figures from this paper

IRON-QUERCETIN COMPLEX REDUCES LIPID AND PROTEIN OXIDATION IN STREPTOZOTOCIN DIABETIC RATS COMPLICATIONS INDEPENDENTLY TO GLUCOSE LOWERING

Investigation of the possible anti-redox effect of ferrous/ferric quercetin complexes on streptozotocin (STZ) diabetic rats during eight weeks of experiment suggests that iron-quercet in gavage enhanced serum total protein, transaminase (AST, ALT) activities and catalase activity in kidney and erythrocyte.

Food Additive (Sodium benzoate)-induced Damage on Renal Function and Glomerular Cells in Rats; Modulating Effect of Aqueous Extract of Atriplex halimus L.

It is demonstrated that Sodium benzoate damages kidney structure and function and is a nephrotoxic substance.

Physalis minima Leaves Extract Induces Re-Endothelialization in Deoxycorticosterone Acetate-Salt-Induced Endothelial Dysfunction in Rats

Investigation of the effects of Physalis minima L. minima leaves extract on serum NO levels, circulating EPCs number, and histopathology of tail artery endothelial cells in DOCA-salt-induced endothelial dysfunction in rats found it dose-dependently increases NO bioavailability contributing to enhanced E PCs mobilization, thereby promoting re-endothelialization inDOCA- salt- induced endothelialfunction in rats.

EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY OF A TRITEREPNE ISOLATED FROM MADHUCA LONGIFOLIA L LEAVES

Objective: To evaluate methanolic extract and dMA of Madhuca longifolia L leaves for possible antioxidant potential. Methods: In vitro antioxidant activity of the methanolic extract and derivative of

References

SHOWING 1-10 OF 36 REFERENCES

Rutin synthase in fava d'anta: purification and influence of stressors.

The flavonoid rutin is synthesized in plants from quercetin, via a process in which isoquercitrin is an intermediary metabolite. In this work, the activities of isoquercitrin synthase and rutin

Ingested quercetin but not rutin increases accumulation of hepatic beta-carotene in BALB/c mice.

It is demonstrated that quercetin can suppress the conversion of beta-carotene which develops in the cytosol of small intestinal epithelial cells, and that r Rutin whose rutinose-moiety prevents being absorbed in the small intestine cannot suppressing the conversion in vivo.

PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITIES OF TWO SELECTED 'BIHI' FRUITS USED AS VEGETABLES IN DARJEELING HIMALAYA

The aim of this study was to determine the antioxidant activity as well as total phenol (TPC) and total flavonoid content (TFC) in two fruits, Solanum anguivi and Solanum incanum grown in Darjeeling

Induction of diabetes by Streptozotocin in rats

Sampling and staining of pancreas tissue of diabetic and normal rats showed that the Langerhans islet beta cells of diabetic rats have been clearly degenerated, and Streptozotocin was used for experiments in induction of experimental diabetes mellitus.

Healing of chronic gastric ulcers in diabetic rats treated with native aspirin, nitric oxide (NO)-derivative of aspirin and cyclooxygenase (COX)-2 inhibitor.

  • I. BrzozowskaA. Targosz E. Hahn
  • Medicine, Biology
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
  • 2004
Ulcer healing is dramatically impaired in experimental diabetes and this effect involves the fall in the gastric microcirculation at the ulcer margin and increased release of proinflammatory cytokines, suggesting that both COX isoforms, namely, COX-1 andCOX-2, are important sources of PG during ulcer healing in diabetes.

Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase.

The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.

Nitric oxide as a mediator of the laxative action of magnesium sulphate

Oral magnesium sulphate produces diarrhoea in rats by increasing the accumulation of fluid in the intestinal lumen and enhancing flow from the proximal to distal intestine, probably through stimulation of the constitutive form of NO synthase.