• Corpus ID: 37858694

EVALUATION OF ANTIDIABETIC AND ANTIHYPERLIPEDEMIC POTENTIAL OF AQUEOUS EXTRACT OF MORINGA OLEIFERA IN FRUCTOSE FED INSULIN RESISTANT AND STZ INDUCED DIABETIC WISTAR RATS: A COMPARATIVE STUDY

@inproceedings{Divi2012EVALUATIONOA,
  title={EVALUATION OF ANTIDIABETIC AND ANTIHYPERLIPEDEMIC POTENTIAL OF AQUEOUS EXTRACT OF MORINGA OLEIFERA IN FRUCTOSE FED INSULIN RESISTANT AND STZ INDUCED DIABETIC WISTAR RATS: A COMPARATIVE STUDY},
  author={Sai Mangala Divi and Ramesh Bellamkonda and Sarala Kumari Dasireddy},
  year={2012}
}
The aim of the present study was to evaluate the effect of aqueous extract of Moringa Oleifera leaves on body weight, plasma glucose, insulin, lipid profile, HOMA and Oral Glucose Tolerance Test in Insulin resistant (IR) and type 1 diabetic rat models. IR was induced by high fructose diet and type 1 diabetes was induced by intraperitoneal injection of Streptozotocin (55 mg / kg body weight). The extract was administered at a dose of 200 mg/ kg body weight by oral intubation for a period of 60… 
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Methods Citations
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67 Citations

ANTIDIABETIC AND ANTIOXIDANT POTENTIAL OF HYDROALCOHOLIC EXTRACT OF MORINGA OLEIFERA LEAVES IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
TLDR
Oral administration of MOLEt showed significant reduction in blood glucose and HbA1c levels and an elevation in serum insulin and hepatic glycogen levels and the extract treatment also reduced TBARS levels and improved the levels of antioxidant markers in the pancreas.
Phytochemical Analysis and Antidiabetic Effect of Aqueous and Ethanolic Extracts of Moringa Oleifera Leaves in Alloxan-Induced Diabetic Wistar Albino Rats Using Insulin as Reference Drug
TLDR
The analysis showed that Moringaoleifera is rich in bioactive agents that enhanced its use as medicinal plant and showed a significant decrease in blood glucose level of the induced rats at 3, 9 and 14 days for aqueous and ethanolic extracts of M.olesifera respectively.
EFFECT OF MOMORDICA CHARANTIA FRUITS ON STREPTOZOTOCIN-INDUCED DIABETES MELLITUS AND ITS ASSOCIATED COMPLICATIONS
TLDR
The in vitro study of L6 cells revealed that the aqueous fraction significantly increased glucose uptake by treated cells by upregulating the expression of IRS, AKT and GLUT4 at both mRNA and protein level.
EFFECT OF TERMINALIA BELERICA FRUITS ON STREPTOZOTOCIN-INDUCED DIABETES MELLITUS AND ITS
TLDR
The findings suggest that the butanol fraction of 95% ethanol extract of Terminalia belerica fruits is competent in combating various symptoms and complications of diabetes mellitus.
Hypoglycemic Potential of Aqueous Extract of Moringa oleifera Leaf and In Vivo GC-MS Metabolomics
TLDR
The aqueous extract of M. oleifera leaf remarkably inhibited the activity of α-amylase and α-glucosidase and it displayed improved antioxidant capacity, glucose tolerance and rate of glucose uptake in yeast cell, suggesting it can be used as phytopharmaceuticals for the management of diabetes by using as adjuvants or alone.
Effect of Moringa oleifera consumption on diabetic rats
TLDR
These results help to increase information over the most popular use of M. oleifera and its safety, however there are needed more studies over the hypoglycemic mechanisms and effects over intestinal microbiota.
Moringa oleifera Lam. (family Moringaceae) leaf extract attenuates high-fat diet-induced dyslipidemia and vascular endothelium dysfunction in Wistar albino rats
TLDR
MEMO treatment produces dose-dependent improvement in lipid profile and vascular endothelium protection, thereby rationalizing its traditional medicine use in the treatment of dyslipidemia and cardiovascular related endothelial disorders.
Amelioration of Hepatic Lipid Peroxidation and Insulin Sensitivity by an Ethanolic Extract of Moringa oleifera in Non-Alcoholic Fatty Liver Disease (NAFLD) in Rats
TLDR
It is suggested that EEMO improves the hepatic status of animals with NAFLD, and also increases the Homeostasis Model Assessment for insulin resistance, serum insulin and fasting blood glucose levels, suggesting diminished insulin sensitivity.
Moringa oleifera Lam. prevents the development of high fructose diet-induced fatty liver
STUDIES ON ANTIDIABETIC EFFECT OF AQUEOUS AND ALCOHOLIC EXTRACTS OF MORINGA OLEIFERA IN STREPTOZOTOCIN INDUCED DIABETIC RATS
STUDIES ON ANTIDIABETIC EFFECT OF AQUEOUS AND ALCOHOLIC EXTRACTS OF MORINGA OLEIFERA IN STREPTOZOTOCIN INDUCED DIABETIC RATS” Name of student Name of Major Advisor Hetal B. Karetha Dr. A. M. Thaker…
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TLDR
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