ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target.

@article{Demir2011ETSdomainTF,
  title={ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target.},
  author={O. Koray Demir and Neşe Ayşit and Zeynep Onder and Nezaket Turkel and Gurkan Ozturk and Andrew D Sharrocks and Isil Aksan Kurnaz},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1812 6},
  pages={652-62}
}
Elk-1 belongs to the ternary complex factors (TCFs) subfamily of the ETS domain proteins, and plays a critical role in the expression of immediate-early genes (IEGs) upon mitogen stimulation and activation of the mitogen-activated protein kinase (MAPK) cascade. The association of TCFs with serum response elements (SREs) on IEG promoters has been widely studied and a role for Elk-1 in promoting cell cycle entry has been determined. However, the presence of the ETS domain transcription factor Elk… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 42 references

SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1

The Journal of cell biology • 2004
View 4 Excerpts
Highly Influenced

Rescue of the spinal muscular atrophy phenıtype in amouse model by early postnatal delivery of SMN

K. D. Foust, X.Wang, +7 authors B. K. Kaspar
Nat Biotech • 2010
View 1 Excerpt

Wildtype Elk-1

O. Demir, I. Aksan Kurnaz
but not a SUMOylation mutant, represses egr-1 expression in SH-SY5Y neuroblastomas, Neurosci. Lett. 437 • 2008
View 2 Excerpts

A TAT-DEF-Elk-1 peptide regulates the cytonuclear trafficking of Elk-1 and controls cytoskeleton dynamics.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2007
View 1 Excerpt

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