ETIOLOGY OF EPIDEMIC ENCEPHALITIS: ITS RELATION TO HERPES, EPIDEMIC POLIOMYELITIS AND POST-VACCINAL ENCEPHALOPATHY

@article{LevaditiETIOLOGYOE,
  title={ETIOLOGY OF EPIDEMIC ENCEPHALITIS: ITS RELATION TO HERPES, EPIDEMIC POLIOMYELITIS AND POST-VACCINAL ENCEPHALOPATHY},
  author={C. Levaditi},
  journal={Journal of Nervous and Mental Disease},
  volume={22},
  pages={767-803}
}
  • C. Levaditi
  • Published 1 October 1929
  • Medicine
  • Journal of Nervous and Mental Disease
ETIOLOGY AND PATHOGENESIS OF EPIDEMIC ENCEPHALITIS; ITS RELATION TO HERPES No problem has given rise to so much activity or to so many publications as that of the etiology of epidemic encephalitis. It is not my intention to make a complete bibliographic survey of the question, nor would this be in harmony with the spirit of the work undertaken by the Matheson Foundation. I shall give, as briefly as possible, a summary of my own researches, in order to uphold, by the aid of definite and… 
8 Citations
ETIOLOGIC SIGNIFICANCE OF STREPTOCOCCI IN EPIDEMIC ENCEPHALITIS: I. INCIDENCE OF STREPTOCOCCI IN CULTURES FROM PATIENTS WITH ENCEPHALITIS IN ST. LOUIS AND FROM NORMAL CONTROLS, AND CHARACTERISTICS OF THE VARIOUS STRAINS ISOLATED
The outbreak of acute epidemic encephalitis in St. Louis in the summer of 1933 offered an especially propitious opportunity to investigate the etiologic importance of streptococci in this disease as
Epidemic Encephalitis and American Neurology, 1919-1940
  • K. Kroker
  • Medicine, Psychology
    Bulletin of the history of medicine
  • 2004
TLDR
A variety of forces influencing the fate of encephalitis lethargica's epidemic status can be seen at work in the Matheson Commission, whose members hoped to use it as a model disease that might supplant their reliance on clinical phenomenology with a causal analysis of nervous disease grounded in the laboratory.
INFLAMMATORY DISEASE OF THE CENTRAL NERVOUS SYSTEM: SO-CALLED NONSUPPURATIVE ENCEPHALITIS AND ENCEPHALOMYELITIS
TLDR
It is obvious that terms such as encephalitis, encephalomyelitis and similar designations, adapted for inflammatory diseases in the various subdivisions of the central nervous system, are of doubtful service without a precise knowledge of what constitutes inflammation, unless the morphologic symptom complex of the so-called inflammatory disease of thecentral nervous system is clearly defined.
SUBACUTE PRIMARY DIFFUSE ENCEPHALITIS: With Marked Involvement of the Right Central Cortical Region in a Child Aged 10
A solution of the problem of the interrelationship of the known diseases of the central nervous system has been offered by various classifications. Spielmeyer, 1 however, commented on the difficulty
RELATION OF FILTRABLE VIRUSES TO DISEASES OF THE NERVOUS SYSTEM
TLDR
Either workers in the virus field must become neuro Pathologists or neuropathologists must learn more about virus disorders of the brain, cord and nerves to end the confusion.
Tic douloureux, Parkinson’s disease and the herpes connection
  • J. S. Howard
  • Medicine, Psychology
    Integrative physiological and behavioral science : the official journal of the Pavlovian Society
  • 1997
TLDR
Evidence characterizing Parkinson’s disease as one of several important manifestations of CNS herpes is covered, with particular attention to the effects of intraneuronal herpes on gasserian ganglion and spinal nuclei discharge threshoolds, as well as viral pathways directly impacting the substantia nigra.
Die entzündlichen Krankheiten des Gehirns und seiner Häute
TLDR
Nur bei groser Ausdehnung wird die unkomplizierte Pachymeningitis externa Hirndruckschwankungen machen, im ubrigen vor allem eine lokale Schmerzhaftigkeit and eigentliche meningeale Symptome erst dann verursachen.

References

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IMMUNOLOGICAL DISTINCTIONS OF ENCEPHALITIS AND POLIOMYELITIS
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  • Medicine
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  • 1921
TLDR
It is regarded as desirable at the present time to hold epidemic poliomyelitis and epidemic encephalitis as integrally distinct affections.
EPIDEMIC (LETHARGIC) ENCEPHALITIS AND ALLIED CONDITIONS
The reappearance of cases of epidemic encephalitis in Europe and America in the last few months has served to emphasize the sinister character, as well as our imperfect knowledge, of the disease.
THE PATHOLOGIC EFFECTS OF STREPTOCOCCI FROM CASES OF POLIOMYELITIS AND OTHER SOURCES
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  • Medicine, Biology
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TLDR
Streptococci cultivated from the tonsils of thirty-two cases of poliomyelitis were used to inoculate various laboratory animals and failed to detect any etiologic or pathologic relationship between strePTococci and epidemic poliomeelitis in man or true experimental poliomersalitis in the monkey.
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The attempt to infect young rabbits and guinea pigs with material containing in all probability the virus of human infantile paralysis failed, and a paralytic disease was observed in young rabbits associated with the presence of an organism showing certain definite characters.