ETA selective receptor antagonism prevents ventricular remodeling in volume-overloaded rats.

@article{Murray2009ETASR,
  title={ETA selective receptor antagonism prevents ventricular remodeling in volume-overloaded rats.},
  author={David B. Murray and Ronald McMillan and Gregory L. Brower and Joseph S Janicki},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2009},
  volume={297 1},
  pages={H109-16}
}
The objective of this study was to investigate the ability of selective endothelin receptor subtype A (ET(A)) endothelin receptor antagonism (ETA) to prevent the acute myocardial remodeling process secondary to volume overload. Left ventricular tissue from sham-operated (Sham) and untreated (Fist), and TBC-3214 (Fist + ETA, 25 mg.kg(-1).day(-1))-treated fistula animals was analyzed for mast cell density, matrix metalloproteinase (MMP) activity, and extracellular collagen volume fraction (CVF) 1… CONTINUE READING
7 Citations
57 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Defective intracellular Ca2 homeostasis contributes to myo H115 ETA ANTAGONISM PREVENTS MAST CELL-INDUCED VENTRICULAR REMODELING AJP-Heart

  • YF Ding, GL Brower, +4 authors J. Zhong
  • Circ Physiol
  • 2009
2 Excerpts

Similar Papers

Loading similar papers…