ESTIMATED EXPOSURE TO PHTHALATES IN COSMETICS AND RISK ASSESSMENT

@article{Koo2004ESTIMATEDET,
  title={ESTIMATED EXPOSURE TO PHTHALATES IN COSMETICS AND RISK ASSESSMENT},
  author={Hyun Jung Koo and Byung Mu Lee},
  journal={Journal of Toxicology and Environmental Health, Part A},
  year={2004},
  volume={67},
  pages={1901 - 1914}
}
  • H. Koo, B. Lee
  • Published 1 December 2004
  • Medicine
  • Journal of Toxicology and Environmental Health, Part A
Some phthalates such as di(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) and their metabolites are suspected of producing teratogenic or endocrine-disrupting effects. To predict possible human exposure to phthalates in cosmetics, the levels of DEHP, diethyl phthalate (DEP), DBP, and butylbenzyl phthalate (BBP) were determined by high-performance liquid chromatography (HPLC) in 102 branded hair sprays, perfumes, deodorants, and nail polishes. DBP was detected in 19 of the 21 nail… 
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An overview of the sources of human phthalate exposure and results of exposure assessments with special focus on human biomonitoring data is presented, and recent findings from animal studies suggest that a cumulative risk assessment for phthalates is warranted.
An Exposure Assessment of DI-(2-Ethylhexyl) Phthalate (DEHP) and DI-n-Butyl Phthalate (DBP) in Human Semen
  • S. Han, H. Lee, B. Lee
  • Medicine, Chemistry
    Journal of toxicology and environmental health. Part A
  • 2009
TLDR
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Reproductive and Developmental Toxicity of Phthalates
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It is concluded that it is important to improve the knowledge of toxic interactions among the different chemicals and to develop measures for combined exposure to various groups of phthalates.
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