ESSENTIAL OILS AS NOVEL HUMAN SKIN PENETRATION ENHANCER FOR TRANSDERMAL DRUG DELIVERY: A REVIEW
@article{Aggarwal2013ESSENTIALOA, title={ESSENTIAL OILS AS NOVEL HUMAN SKIN PENETRATION ENHANCER FOR TRANSDERMAL DRUG DELIVERY: A REVIEW}, author={Shikha Aggarwal and Suraj Prakash Agarwal and Sunny Jalhan}, journal={International journal of pharma and bio sciences}, year={2013} }
Transdermal drug delivery system established itself as an integral part of a novel drug delivery system because of various factors like high bioavailability, absence of first pass metabolism, steady drug plasma concentration. There are many obstacles that do not allow drug to penetrate deeper into the skin. Now a day’s various skin penetration enhancement techniques have been developed to limit this barrier by use of various natural penetration enhancers like essential oils. This review covers…
No Paper Link Available
19 Citations
OILS AS PENETRATION ENHANCERS FOR IMPROVED TRANSDERMAL DRUG DELIVERY: A REVIEW
- Biology
- 2017
The present review reports the role of Natural oils in enhancing the permeation of drugs through skin because of possessing different features like natural origin, favorable penetration enhancement and partitioning action in the skin by the oils.
A Review on Chemical Permeation Enhancers used in the Formulation of Transdermal Drug Delivery System
- Biology, ChemistryJournal of Pharmaceutical Research International
- 2021
Different compounds assessed for improving penetration activity like sulphoxides, azones, pyrrolidones, alcohols and alkanols, glycols, surfactants and terpenes are focused on.
The Impact of Penetration Enhancers on Transdermal Drug Delivery System: Physical and Chemical Approach
- Biology
- 2015
This review presents a comprehensive account of various aspects of drug delivery by transdermal route including the various chemical and physical penetration enhancers.
A NOVEL APPROACH ON TRANSDERMAL DRUG DELIVERY SYSTEM [TDDS]
- Biology
- 2016
This review article covers a brief outline of the Transdermal drug Delivery system, advantages over conventional drug delivery system, Layers of the skin, various components of TransDermal patch, penetration enhancers, and evaluation of Trans Dermal system and applications.
PERMEATION ENHANCEMENT OF MODEL ANTI-HYAPERTENSIVE DRUG FROM TRANSDERMAL PATCHES USING ESSENTIAL OILS
- Engineering
- 2019
The main objective of this study was to develop transdermal Patch of Valsartan using various essential oils which act as permeation enhancer. valsartan is the most widely used antihypertensive drug…
Fabrication of Transdermal Matrix Patch of Lercanidipine Hydrochloride Using Natural Polymer and Essential Oil
- EngineeringJournal of Pharmaceutical Research International
- 2022
The goal of the present research work was to develop and characterize a transdermal matrix patch of Lercanidipine hydrochloride (L.H.) for controlled drug delivery using the solvent evaporation…
Systematic Review on the Effectiveness of Essential and Carrier Oils as Skin Penetration Enhancers in Pharmaceutical Formulations
- ChemistryScientia Pharmaceutica
- 2022
Oils, including essential oils and their constituents, are widely reported to have penetration enhancement activity and have been incorporated into a wide range of pharmaceutical formulations. This…
In vitro percutaneous absorption studies of cannabidiol using human skin: Exploring the effect of drug concentration, chemical enhancers, and essential oils.
- Biology, MedicineInternational journal of pharmaceutics
- 2022
Annona muricata extract containing pharmaceutical emulgels with and without penetration enhancer for depigmenting and antierythmic effects.
- Chemistry, MedicinePakistan journal of pharmaceutical sciences
- 2018
This study reveals that the Annona muricata L. fruit extract naturally contains some important phenolic compounds and can be effectively used in topical preparations for the treatment of skin hyperpigmentation and dermatitis.
References
SHOWING 1-10 OF 28 REFERENCES
PENETRATION ENHANCERS: A NOVEL STRATEGY FOR ENHANCING TRANSDERMAL DRUG DELIVERY
- Biology
- 2012
Terpenes are included in the list of Generally Recognized as Safe (GRAS) substances and have low irritancy potential and are used as an aid in potential clinical applications.
Transdermal drug delivery: penetration enhancement techniques.
- BiologyCurrent drug delivery
- 2005
Skin penetration enhancement techniques based on drug/vehicle optimisation such as drug selection, prodrugs and ion-pairs, supersaturated drug solutions, eutectic systems, complexation, liposomes, vesicles and particles are described.
A Review: Transdermal Drug Delivery System: A Tool For Novel Drug Delivery System
- Biology
- 2011
The present review article explores the overall study on transdermal drug delivery system (TDDS) which leads to novel drug Delivery System (NDDS), and investigates the role of skin penetration enhancement techniques in this development.
Mechanism of in vitro percutaneous absorption enhancement of carvedilol by penetration enhancers.
- ChemistryPharmaceutical development and technology
- 2008
Results indicated that the black cumin oil shows its action by extraction of lipids from stratum corneum as well as by loosening the hydrogen bonds between ceramides subsequently leading to fluidization of the lipid bilayer.
TRANSDERMAL DRUG DELIVERY SYSTEM: REVIEW
- Biology
- 2012
Transdermal drug delivery is a recent technology which promises a great future it has a potential to limit the use of needles for administering wide variety of drugs but cost factor is a important thing to consider since developing nations like India have second highest population, but due to higher cost TDDS are the hidden part of therapy used in general population.
Innovative Strategies for Enhancing Topical and Transdermal Drug Delivery
- Biology
- 2007
Strategies developed to enhance the skin penetration of drugs, ranging from conventional approaches, for example the use of chemical penetration enhancers to those in early-stage development, such as microscissioning are reviewed.
Effect of Different Terpene-Containing Essential Oils on Percutaneous Absorption of Trazodone Hydrochloride Through Mouse Epidermis
- Chemistry, MedicineDrug delivery
- 2006
Results showed that pretreatment of skin with essential oils increases the flux values of TZN compared with the values obtained when the same essential oils were included in the transdermal devices.
Effect of different terpene-containing essential oils on permeation of estradiol through hairless mouse skin.
- Chemistry, BiologyInternational journal of pharmaceutics
- 2002
Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review
- ChemistryPhytotherapy research : PTR
- 2007
The possible role and mode of action of these natural products is discussed with regard to the prevention and treatment of cancer, cardiovascular diseases including atherosclerosis and thrombosis, as well as their bioactivity as antibacterial, antiviral, antioxidants and antidiabetic agents.