ESR1 gene amplification in endometrial carcinomas: a clinicopathological analysis.

@article{Rahman2013ESR1GA,
  title={ESR1 gene amplification in endometrial carcinomas: a clinicopathological analysis.},
  author={Mohammed Tanjimur Rahman and Kentaro Nakayama and Munmun Rahman and Masako Ishikawa and Hiroshi Katagiri and Atsuko Katagiri and Tomoka Ishibashi and Emi Sato and Kouji Iida and Noriyuki Ishikawa and Naomi Nakayama and Kohji Miyazaki},
  journal={Anticancer research},
  year={2013},
  volume={33 9},
  pages={3775-81}
}
This study investigated the clinicopathological significance of estrogen receptor 1 (ESR1) gene amplification and its relationship to phosphatase and tensin homolog (PTEN), human epidermal growth factor receptor 2 (HER2), MutL homolog 1 (MLH1), p53, and AT rich interactive domain 1A (ARID1A) expression in endometrial carcinomas. ESR1 amplification and expression were assessed by fluorescence in situ hybridization and immunohistochemistry. Clinical data were collected by retrospective chart… CONTINUE READING