ESE-1 inhibits the invasion of oral squamous cell carcinoma in conjunction with MMP-9 suppression.

@article{Iwai2008ESE1IT,
  title={ESE-1 inhibits the invasion of oral squamous cell carcinoma in conjunction with MMP-9 suppression.},
  author={So-ichi Iwai and Shigeki Amekawa and Kentaro Yomogida and Tadateru Sumi and Mituhiro Nakazawa and Yoshiaki Yura and Yoshitake Nishimune and Masami Nozaki},
  journal={Oral diseases},
  year={2008},
  volume={14 2},
  pages={144-9}
}
OBJECTIVES Matrix metalloproteinases (MMPs) regulated by ets transcription factors facilitate carcinoma cell invasion. An ets family member, ESE-1, is expressed specifically in epithelial tissues, but its association with MMPs is obscure. In this study, we investigated whether ESE-1 regulates invasion of oral squamous cell carcinoma (SCC) via transcriptional activity of MMP-9. METHODS HSC-3 and KB were used as human oral SCC lines. The expression of ESE-1 and MMP-9 was detected by in situ… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…