ERrrr…Where are the Progenitors? Hormone Receptors and Mammary Cell Heterogeneity

@inproceedings{Tornillo2015ERrrrWhereAT,
  title={ERrrr…Where are the Progenitors? Hormone Receptors and Mammary Cell Heterogeneity},
  author={Giusy Tornillo and M. H. A. P. Robert J. Smalley},
  booktitle={Journal of Mammary Gland Biology and Neoplasia},
  year={2015}
}
The mammary epithelium is a highly heterogenous and dynamic tissue that includes a range of cell types with varying levels of proliferative capacity and differentiation potential, from stem to committed progenitor and mature cells. Generation of mature cells through expansion and specification of immature precursors is driven by hormonal and local stimuli. Intriguingly, although circulating hormones can be directly sensed only by a subset of mammary cells, they also regulate the behaviour of… CONTINUE READING
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