ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase.

  title={ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase.},
  author={Helen Coe and Marek Michalak},
  journal={The international journal of biochemistry & cell biology},
  volume={42 6},
ERp57 is a 58-kDa thiol oxidoreductase and a member of the protein disulfide isomerase (PDI)-like family. ERp57 is highly similar to other PDI family members in terms of amino acid sequence and structural/functional domain organization; however, it possesses some distinctive structural features that dictate its unique functions in the cell. This protein plays an important role in endoplasmic reticulum quality control of newly synthesized glycoproteins, is critical in major histocompatability… CONTINUE READING
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