ERp 72 , an Abundant Luminal Endoplasmic Reticulum Protein , Contains Three Copies of the Active Site Sequences of Protein Disulfide Isomerase *

@inproceedings{Sherry2001ERp7,
  title={ERp 72 , an Abundant Luminal Endoplasmic Reticulum Protein , Contains Three Copies of the Active Site Sequences of Protein Disulfide Isomerase *},
  author={Sherry and M.. and Haugejorden and Michael and Green},
  year={2001}
}
We have cloned, sequenced, and expressed full length cDNA clones encoding two abundant, luminal endoplasmic reticulum proteins (ERp), ERp59/PDI and ERp72. ERp59/PDI has been identified as the microsomal enzyme protein disulfide isomerase (PDI). An analysis of the amino acid sequence of ERp72 showed that it shared sequence identity with ERp59/PDI at three discrete regions, having three copies of the sequences that are thought to be the CGHC-containing active sites of ERp59/PDI. Thus, ERp72… CONTINUE READING