ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

Abstract

At birth, the heart undergoes a critical metabolic switch from a predominant dependence on carbohydrates during fetal life to a greater dependence on postnatal oxidative metabolism. This remains the principle metabolic state throughout life, although pathologic conditions such as heart failure and cardiac hypertrophy reactivate components of the fetal… (More)

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Cite this paper

@article{Alaynick2007ERRgammaDA, title={ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.}, author={William A. Alaynick and Richard P. Kondo and Wen Xie and Weimin He and Catherine Rosa Dufour and M Beverly Downes and Johan W. Jonker and Wayne H. Giles and Robert K. Naviaux and Vincent Gigu{\`e}re and Ronald M Evans}, journal={Cell metabolism}, year={2007}, volume={6 1}, pages={13-24} }