ERM proteins in epithelial cell organization and functions.

  title={ERM proteins in epithelial cell organization and functions.},
  author={Bruno Fi{\'e}vet and Daniel Louvard and Monique Arpin},
  journal={Biochimica et biophysica acta},
  volume={1773 5},
ERM (Ezrin, Radixin, Moesin) proteins are membrane-cytoskeleton linkers that regulate the structure and the function of specific domains of the plasma membrane. ERM proteins are expressed in all metazoan analyzed so far. Genetic analysis of ERM protein functions has recently been performed simultaneously in three different organisms, mouse, Drosophila melanogaster and C. elegans. These studies have revealed a remarkable conservation of the protein functions through evolution. Moreover they have… CONTINUE READING

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