ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss

@inproceedings{Kurioka2015ERK2MI,
  title={ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss},
  author={Takaomi Kurioka and Takeshi Matsunobu and Yasushi Satoh and Katsuki Niwa and Shogo Endo and Masato Fujioka and Akihiro Shiotani},
  booktitle={Scientific reports},
  year={2015}
}
Extracellular signal-regulated kinase (ERK) is a member of the family of mitogen-activated protein kinases (MAPKs) and coordinately regulates a multitude of cellular processes. In response to a variety of extracellular stimuli, phosphorylation of both threonine and tyrosine residues activates ERK. Recent evidence indicates that ERK is activated in response to cellular stress such as acoustic trauma. However, the specific role of ERK isoforms in auditory function is not fully understood. Here… CONTINUE READING
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