ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer

@article{Jerjees2014ERK12IR,
  title={ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer},
  author={Dena A. Jerjees and M. Layth Alabdullah and Methaq Alkaabi and Rezvan Abduljabbar and Abir A. Abdelhadi Muftah and Chris Nolan and Andrew R. Green and Ian O. Ellis and Emad A Rakha},
  journal={Breast Cancer Research and Treatment},
  year={2014},
  volume={147},
  pages={25-37}
}
The extracellular-regulated kinase (ERK) 1/2 is one of the members of the mitogen-activated protein kinases (MAPKs). MAPKs are transduction proteins that play a role in controlling diverse cellular functions including proliferation and survival. In breast cancer (BC), MAPKs are involved in oestrogen receptor (ER) and HER2 pathways. This study aims to assess… CONTINUE READING