ERG rearrangement in local recurrences compared to distant metastases of castration-resistant prostate cancer

@article{Scheble2012ERGRI,
  title={ERG rearrangement in local recurrences compared to distant metastases of castration-resistant prostate cancer},
  author={Veit J. Scheble and Gregor Scharf and Martin Ulrich Braun and Christian Ruiz and Susanna St{\"u}rm and Karen Petersen and Rudi Beschorner and Alexander Bachmann and Tobias Zellweger and Falko Fend and Glen Kristiansen and Lukas Bubendorf and Nicolas Wernert and Zaki Shaikhibrahim and Sven Perner},
  journal={Virchows Archiv},
  year={2012},
  volume={461},
  pages={157-162}
}
Castration-resistant prostate cancer is the second most common cause of cancer death and results in a median survival of less than 2 years. In prostate cancer, fusions between TMPRSS2 and ERG are common. The ERG rearrangement prevalence in local recurrent castration-resistant prostate cancer compared to distant metastatic prostate cancer is unknown. We investigated the frequency of ERG rearrangement in local recurrent castration-resistant prostate cancer compared to distant metastatic prostate… CONTINUE READING