ERG evaluation of daily, high-dose sildenafil usage

@article{Zoumalan2008ERGEO,
  title={ERG evaluation of daily, high-dose sildenafil usage},
  author={Christopher I. Zoumalan and Roham T. Zamanian and Ramona Doyle and Michael F Marmor},
  journal={Documenta Ophthalmologica},
  year={2008},
  volume={118},
  pages={225-231}
}
Purpose Sildenafil can cause transient, mild ERG changes in healthy individuals taking large single doses. Although the drug was originally intended for intermittent use in erectile dysfunction, it has now been approved for chronic use in subjects with pulmonary arterial hypertension (PAH). The purpose of our study is to investigate possible ERG changes in subjects using large doses of sildenafil on a chronic daily basis. Methods We examined five subjects with PAH taking sildenafil daily for 1… CONTINUE READING
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