ERG and SALL4 expressions in SMARCB1/INI1-deficient tumors: a useful tool for distinguishing epithelioid sarcoma from malignant rhabdoid tumor.

@article{Kohashi2015ERGAS,
  title={ERG and SALL4 expressions in SMARCB1/INI1-deficient tumors: a useful tool for distinguishing epithelioid sarcoma from malignant rhabdoid tumor.},
  author={Kenichi Kohashi and Yuichi Nagoya Yamada and Yuka Hotokebuchi and Hidetaka Yamamoto and Takahiro Taguchi and Y. Robert Iwamoto and Yoshinao Oda},
  journal={Human pathology},
  year={2015},
  volume={46 2},
  pages={
          225-30
        }
}
ERG is immunoexpressed in vascular endothelial tumors, blastic extramedullary myeloid tumors, and tumors with ERG-involved translocation, such as prostate carcinoma or Ewing sarcoma. Recently, ERG immunoexpression was reported in an epithelioid sarcoma, which is a SMARCB1/INI1-deficient tumor, although epithelioid sarcoma is not associated with chromosomal translocations involving ERG and is categorized as a tumor with uncertain differentiation. SALL4 is essential for a proliferation and… CONTINUE READING
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