ERDO - a framework to select an appropriate randomization procedure for clinical trials

@inproceedings{Hilgers2017ERDOA,
  title={ERDO - a framework to select an appropriate randomization procedure for clinical trials},
  author={Ralf-Dieter Hilgers and Diane Uschner and William F Rosenberger and Nicole Heussen},
  booktitle={BMC medical research methodology},
  year={2017}
}
BACKGROUND Randomization is considered to be a key feature to protect against bias in randomized clinical trials. Randomization induces comparability with respect to known and unknown covariates, mitigates selection bias, and provides a basis for inference. Although various randomization procedures have been proposed, no single procedure performs uniformly best. In the design phase of a clinical trial, the scientist has to decide which randomization procedure to use, taking into account the… CONTINUE READING