ERCC2 Lys751Gln polymorphism is associated with lung cancer among Caucasians.

@article{Zhang2010ERCC2LP,
  title={ERCC2 Lys751Gln polymorphism is associated with lung cancer among Caucasians.},
  author={Jian Zhang and Shi-yang Gu and Ping Zhang and Zhen Hua Jia and Jian-hua Chang},
  journal={European journal of cancer},
  year={2010},
  volume={46 13},
  pages={2479-84}
}
To derive a more precise estimation of the relationship between the excision repair cross-complementing rodent repair deficiency, group 2 (ERCC2) Lys751Gln polymorphism and lung cancer risk, a meta-analysis was performed. A total of 23 studies including 8137 cases and 9824 controls were involved in this meta-analysis. Overall, significantly elevated lung cancer risk was associated with ERCC2 Gln allele when all studies were pooled into the meta-analysis (Lys/Gln versus Lys/Lys: odds ratio (OR… CONTINUE READING