ERCC1 predicting chemoradiation resistance and poor outcome in oesophageal cancer.

@article{Kim2008ERCC1PC,
  title={ERCC1 predicting chemoradiation resistance and poor outcome in oesophageal cancer.},
  author={Min Kyoung Kim and Kyung-Ja Cho and Gui Young Kwon and Seung Il Park and Yong Hee Kim and Jong Hoon Kim and H-y Song and Ji Hoon Shin and Hwoon Yong Jung and Gin Hyug Lee and Kee Don Choi and Sung- Bae Kim},
  journal={European journal of cancer},
  year={2008},
  volume={44 1},
  pages={54-60}
}
We assessed whether expression of excision repair cross-complementation group 1 (ERCC1) and/or thymidylate synthase (TS) can predict clinical outcome after preoperative chemoradiotherapy (CRT) in patients with localised oesophageal cancer. Paraffin-embedded pretreatment tumour specimens collected by endoscopic biopsy from patients treated with preoperative CRT (5-fluorouracil/cisplatin or capecitabine/cisplatin plus radiation) were analysed by immunohistochemical assay. Between March 1993 and… CONTINUE READING

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