ER-mitochondria communication. How privileged?

  title={ER-mitochondria communication. How privileged?},
  author={Clara Franzini-armstrong},
Mitochondria have a low affinity for Ca(2+), but they take up these ions during normal cell activity because they are in close proximity to the sites of calcium entry into the cell and of internal Ca(2+) release. This gives mitochondria privileged access to cytoplasmic Ca(2+) without requiring a direct communication with the endoplasmic reticulum. 

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