ER-mitochondria communication. How privileged?


Mitochondria have a low affinity for Ca(2+), but they take up these ions during normal cell activity because they are in close proximity to the sites of calcium entry into the cell and of internal Ca(2+) release. This gives mitochondria privileged access to cytoplasmic Ca(2+) without requiring a direct communication with the endoplasmic reticulum.


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@article{Franziniarmstrong2007ERmitochondriaCH, title={ER-mitochondria communication. How privileged?}, author={Clara Franzini-armstrong}, journal={Physiology}, year={2007}, volume={22}, pages={261-8} }