EPLIN-α expression in human oesophageal cancer and its impact on cellular aggressiveness and clinical outcome.

@article{Liu2012EPLINEI,
  title={EPLIN-α expression in human oesophageal cancer and its impact on cellular aggressiveness and clinical outcome.},
  author={Yinan Liu and Andrew James Sanders and Lijian Zhang and Wen Jiang},
  journal={Anticancer research},
  year={2012},
  volume={32 4},
  pages={1283-9}
}
BACKGROUND Epithelial protein lost in neoplasm-α (EPLIN-α) is a cytoskeletal protein whose expression is often lost or is aberrant in cancerous cells and tissues and whose loss is believed to be involved in aggressive phenotype. Our current study examined this molecule in human oesophageal tissues and investigated the cellular impact of EPLIN-α on oesophageal cancer cells. MATERIALS AND METHODS Expression of the EPLIN-α transcript in human oesophageal tissues (tumour, paratumour and normal… CONTINUE READING