EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units

@article{KamThong2011EPIBLASTERfastET,
  title={EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units},
  author={Tony Kam-Thong and Darina Czamara and Koji Tsuda and Karsten Borgwardt and Cathryn M. Lewis and Angelika Erhardt-Lehmann and Bernhard Hemmer and Peter Rieckmann and Markus Daake and Frank Gerd Weber and Christiane Wolf and Andreas Ziegler and Benno P{\"u}tz and Florian Holsboer and Bernhard Sch{\"o}lkopf and Bertram M{\"u}ller-Myhsok},
  journal={European Journal of Human Genetics},
  year={2011},
  volume={19},
  pages={465-471}
}
Detection of epistatic interaction between loci has been postulated to provide a more in-depth understanding of the complex biological and biochemical pathways underlying human diseases. Studying the interaction between two loci is the natural progression following traditional and well-established single locus analysis. However, the added costs and time duration required for the computation involved have thus far deterred researchers from pursuing a genome-wide analysis of epistasis. In this… CONTINUE READING
47 Citations
12 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 12 references

Similar Papers

Loading similar papers…