EPHB receptor signaling in dendritic spine development.

  title={EPHB receptor signaling in dendritic spine development.},
  author={Fumitoshi Irie and Yu Yamaguchi},
  journal={Frontiers in bioscience : a journal and virtual library},
Dendritic spines are small bulbous protrusions on the surface of dendrites that serve as principle postsynaptic targets for excitatory synapses (1-3). Structural modifications of dendritic spines have been implicated as a cellular basis for learning and memory. Morphological abnormalities of spines are observed in some neurological diseases such as mental retardation and schizophrenia (4). Thus, studies on the morphological regulation of dendritic spines could have strong relevance to our… CONTINUE READING