EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality.

@article{Gustafsson2007EP14SC,
  title={EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality.},
  author={Annika Gustafsson and Elisabeth Hansson and Ulf Kressner and Svante Nordgren and Marianne Andersson and Wenhua Wang and Christina L{\"o}nnroth and Kent G Lundholm},
  journal={International journal of cancer},
  year={2007},
  volume={121 2},
  pages={232-40}
}
The importance of prostaglandins in tumor growth and progression is well recognized, including antineoplastic activities by cyclooxygenase (COX) inhibitors. Variation in treatment response to COX inhibition has questioned differences in expression of cell surface and nuclear membrane receptors among tumors with different disease progression. The purpose of this study was to evaluate whether EP(1-4) subtype, PPAR gamma receptor and COX-1/COX-2 expression in colorectal cancer are related to tumor… CONTINUE READING