ENDOTOXIN-INDUCED CHANGES IN SLEEP AND SLEEPINESS DURING THE DAY

@article{Hermann1998ENDOTOXININDUCEDCI,
  title={ENDOTOXIN-INDUCED CHANGES IN SLEEP AND SLEEPINESS DURING THE DAY},
  author={Dirk M Hermann and Janet Mullington and Dunja Hinze-Selch and Wolfgang Dipl Ing Schreiber and Thomas Pollm{\"a}cher},
  journal={Psychoneuroendocrinology},
  year={1998},
  volume={23},
  pages={427-437}
}
Sleepiness is a common symptom of infectious diseases. However, the peculiarities and causes of impaired vigilance during host defense activation are largely unknown. It has been shown earlier that mild host defense activation by endotoxin does not affect daytime sleepiness and non-rapid eye movement (NREM) sleep in humans. In the present study we investigated the effects of a more intensive stimulation of the host defense by Salmonella abortus equi endotoxin (0.8 ng/kg), administered 12 h… CONTINUE READING
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