ENDOR studies of VO2+: probing protein-metal ion interactions in nephrocalcin.


Nephrocalcin inhibits the growth of calcium oxalate monohydrate crystals in the mammalian kidney. Isoforms A and B contain three equivalents of gamma-carboxyglutamic acid (Gla) residues implicated in Ca2+-binding and exhibit strong inhibitor properties and high Ca2+-binding affinity (Kd approximately 10(-8) M). Isoforms C and D lack these properties and… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.