ENDOCRINE HISTORY: The history of discovery, synthesis and development of testosterone for clinical use.

@article{Nieschlag2019ENDOCRINEHT,
  title={ENDOCRINE HISTORY: The history of discovery, synthesis and development of testosterone for clinical use.},
  author={Eberhard Nieschlag and Susan Nieschlag},
  journal={European journal of endocrinology},
  year={2019},
  volume={180 6},
  pages={
          R201-R212
        }
}
As the most important male hormone, testosterone has an impact on almost all organs and body functions. The biological effects of testosterone and the testes have been known since antiquity, long before testosterone was identified as the active agent. Practical applications of this knowledge were castration of males to produce obedient servants, for punishment, for preservation of the prepubertal soprano voice and even for treatment of diseases. Testes were used in organotherapy and… 

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