ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein.

@article{Hernndez1997ENC1AN,
  title={ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein.},
  author={M C Carre{\~n}o Hern{\'a}ndez and Pedro J. Andres-Barquin and Salvador Martinez and Alessandro Bulfone and John L R Rubenstein and Mark A. Israel},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1997},
  volume={17 9},
  pages={3038-51}
}
We have identified and characterized a novel murine gene, Ectoderm-Neural Cortex-1 (ENC-1), that is an early and highly specific marker of neural induction in vertebrates. ENC-1, which encodes a kelch family related protein, is expressed during early gastrulation in the prospective neuroectodermal region of the epiblast and later in development throughout the nervous system (NS). ENC-1 expression is highly dynamic and, after neurulation, preferentially defines prospective cortical areas. The… CONTINUE READING

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