EMLA cream and nitrous oxide to alleviate pain induced by palivizumab (Synagis) intramuscular injections in infants and young children.

@article{Carbajal2008EMLACA,
  title={EMLA cream and nitrous oxide to alleviate pain induced by palivizumab (Synagis) intramuscular injections in infants and young children.},
  author={Ricardo Palma Carbajal and Valerie Biran and Richard Lenclen and Ralph Epaud and Patricia Cimerman and Pascale Wanquet Thibault and Mireille Nathanson and Francis Gold and Brigitte Fauroux},
  journal={Pediatrics},
  year={2008},
  volume={121 6},
  pages={
          e1591-8
        }
}
OBJECTIVE Palivizumab (Synagis [Abbot Laboratories, Kent, United Kingdom]) is recommended for the prevention of severe lower respiratory tract infections caused by respiratory syncytial virus in infants at high risk. These injections are very painful, and currently the use of analgesics is not systematic. The objective of this study was to compare the efficacy of EMLA with premixed 50% nitrous oxide/oxygen, used alone or combined with EMLA, for pain alleviation during palivizumab injections… CONTINUE READING
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