EML4-ALK fusion gene assessment using metastatic lymph node samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration.

@article{Sakairi2010EML4ALKFG,
  title={EML4-ALK fusion gene assessment using metastatic lymph node samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration.},
  author={Yuichi Sakairi and Takahiro Nakajima and Kazuhiro Yasufuku and Dai Ikebe and Hajime Kageyama and Manabu Soda and Kengo Takeuchi and Makiko Itami and Toshihiko Iizasa and Ichiro Yoshino and Hiroyuki Mano and Hideki Kimura},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2010},
  volume={16 20},
  pages={4938-45}
}
PURPOSE Anaplastic lymphoma kinase (ALK) fusion genes represent novel oncogenes for non-small cell lung cancers (NSCLC). Several ALK inhibitors have been developed, and are now being evaluated in ALK-positive NSCLC. The feasibility of detecting ALK fusion genes in samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was determined. The clinicopathologic characteristics of ALK-positive lung cancer were also analyzed. EXPERIMENTAL DESIGN From April… CONTINUE READING
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