EMAST Is Associated with a Poor Prognosis in Microsatellite Instable Metastatic Colorectal Cancer

@inproceedings{Venderbosch2015EMASTIA,
  title={EMAST Is Associated with a Poor Prognosis in Microsatellite Instable Metastatic Colorectal Cancer},
  author={Sabine Venderbosch and Shannon van Lent—van Vliet and Anton F J de Haan and Marjolijn J. L. Ligtenberg and Monique Goossens and Cornelis J A Punt and Miriam Koopman and Iris Nagtegaal},
  booktitle={PloS one},
  year={2015}
}
PURPOSE To determine the frequency and prognostic value of elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) in metastatic colorectal cancer (mCRC) patients in relation to microsatellite instability (MSI) status and MSH3 protein expression. MATERIAL AND METHODS The frequency of EMAST was evaluated in mCRC patients with MSI tumors and microsatellite stable (MSS) tumors. A literature overview was performed to compare the frequency of EMAST in our study with… CONTINUE READING

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