ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division.

@article{Rasala2006ELYSIA,
  title={ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division.},
  author={Beth A. Rasala and Arturo V. Orjalo and Zhouxin Shen and Steven Briggs and Douglass J. Forbes},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 47},
  pages={17801-6}
}
Nuclear pores span the nuclear envelope and act as gated aqueous channels to regulate the transport of macromolecules between the nucleus and cytoplasm, from individual proteins and RNAs to entire viral genomes. By far the largest subunit of the nuclear pore is the Nup107-160 complex, which consists of nine proteins and is critical for nuclear pore assembly. At mitosis, the Nup107-160 complex localizes to kinetochores, suggesting that it may also function in chromosome segregation. To… CONTINUE READING
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